Photodynamic Therapy for Barrett's Esophagus and Esophageal Carcinoma
نویسندگان
چکیده
This paper reviews the use of photodynamic therapy (PDT) in patients with Barrett's esophagus and esophageal carcinoma. We describe the history of PDT, mechanics, photosensitizers for PDT in patients with esophageal disease. Finally, we discuss its utility and limitations in this setting.
منابع مشابه
Photodynamic therapy of Barrett's esophagus.
Photodynamic therapy seems to be able to control high-grade dysplasia within Barrett's esophagus about 80% of the time. Long-term results are not available, but the treatment is promising. Given the success with surgical intervention, however, use of photodynamic therapy should be reserved for nonsurgical candidates at the current time. The complications that occur with photodynamic therapy are...
متن کاملPorfimer sodium photodynamic therapy for management of Barrett's esophagus with high-grade dysplasia.
Porfimer sodium photodynamic therapy (ps-PDT) for Barrett's esophagus is a powerful endoscopic treatment that can eliminate high-grade dysplasia (HGD) and Barrett's mucosa and reduce the risk of development of cancer in these patients. Ps-PDT typically results in destruction of Barrett's esophagus in the majority of the treated area. However, residual small island of Barrett's mucosa may persis...
متن کاملفراوانی مری بارت دربیماران کاندید انجام آندوسکوپی
Background : Barrett's esophagus is a precancerous lesion leading to esophageal carcinoma in 10% of cases. It is usually remained undetected during endoscopy and most of physicians do not take biopsy from gastroesophageal junction (GEJ) when it seems to be normal. In the present study we have determined the frequency of Barrett's esophagus in a group of Iranian patients referring for endoscopy ...
متن کامل[Endoscopic therapy for Barrett's esophagus].
There are many foreign reports about the endoscopic ablation therapy for Barrett's esophagus. Endoscopic ablation therapy include thermal therapy (electrocoagulation, laser etc.), photodynamic therapy or endoscopic resection and so on. Ablation of Barrett's esophagus by these therapy in combination with adequate acid suppression lead to mucosal replacement by squamous epithelium. But the true v...
متن کاملPilot study on light dosimetry variables for photodynamic therapy of Barrett's esophagus with high-grade dysplasia.
PURPOSE Photodynamic therapy (PDT) is used to treat Barrett's esophagus with high-grade dysplasia and mucosal carcinoma. Outcomes are variable with some patients having persistent disease, whereas others develop strictures. The aims of this study were (a) to compare porfimer sodium tissue uptake, light dose, and esophageal thickness with clinical outcomes and (b) to determine the selectivity of...
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عنوان ژورنال:
دوره 46 شماره
صفحات -
تاریخ انتشار 2013